News...
| Perdix joins the EU "InSight" project | March 12th, 2011 |
Perdix has become member of the EU project "InSight". This project aims on the development of on-line measurement of nano-particles based on various principles. Perdix contribtion to the project is to push the optical resolution of its probe technology beyond the 1 micron barrier.
| Coming soon: 19mm Standard Probes / OPC connectivity | January 5th, 2011 |
Around the summer of this year, Perdix will introduce a 19mm diameter standard probe with 2.5 micron optical resolution. This probe will fill the demand for probes that fit in standard reactors with 19mm holes.
| Introduction of longer ISPV Standard Probe | October 16th, 2009 |
For use in larger pilot reactors, Perdix has introduced a longer version of the standard probes. The wet part of these probes is extended from 270mm to 1060mm. These probes have a diameter of 25mm and an optical resolution of 10 micron
| Development of in-line probe for DSTI project: "Control of Pharma batch crystallization" | May 19th, 2010 |
The board of the DSTI project "Control of Pharma batch crystallization" has selected Perdix for developing in-line imaging flow-cells for measuring particle size and shape. This project aims to develop and demonstrate a model predictive control system for batch crysallization. It is based on skid with measurement equipment for measuring key parameters of the process and a model predictive controller for steering the cooling and mixing profile of the process. Two ISPV flow-cells with different optical magnifications will be used to measure real-time the particle size distribution and shape parameters of the crystals for determining the morphology of the crystals.
| DSTI Techno-project was succesfully finished | February 25th, 2010 |
Perdix has started a validation project under the hood of DSTI, the Dutch Separation Institute. The aim of the project was to validate if it is possible not only to view a commercial batch crystallization process, but also to measure the particle size distribution during the crystallization. The validation was carried out in a pharmaceutical lactose batch cooling crystallization and a large ISPV probe (ISPV-N-XL). The final conclusions of the validation:
- For low concentrations (less 5%) the turbidity signal and the PSD seem to be accurate
- The images made with the probe are valuable for understanding the crystallization process
- No encrustration occurred during the crystallization
| Avantium Crystalline now available | February 10th, 2009 |
Avantium has proudly released the Crystalline instrument. This instrument is designed for high-throughput research on crystallization processes. It features 4 reactors that can be operated simultaneously . Next to a turbidity measurement, an optional imaging unit and/or a Raman spectrocopy unit can be connected to the Crsytalline. The imaging unit and the image analysis software are designed/licensed by Perdix based on its proprietary ISPV technology